Metabolic Syndrome among Asian Indian children
- The metabolic syndrome (MS) in children is an important clinical marker of diabetes and coronary artery disease (CAD) in young adulthood.1
- There is an alarming increase in MS in Indian children that parallel the obesity.2Insulin resistance, the underlying pathophysiology of MS is reported to be present in nearly 30 per cent of children and adolescents in India, more so in girls.2
- South Asian children have higher blood pressure levels than white children at every BMI categories in the United States.4
- Obese children in Malaysia are at a greater risk of developing MS, with Indian children having higher risk than Chinese and Malays.5
- Exercise training improves insulin sensitivity and endothelial vascular function beyond the benefits of glycemic control and blood pressure reduction in adults and children.9
- Early intervention aimed at managing obesity could reduce the risk of developing the MS. It is conceivable that even in the absence of weight loss, overweight and obese children may improve their cardiovascular risk profile by lifestyle changes and therapies targeted toward individual components of the syndrome.10
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10. Steinberger J, Daniels SR, Eckel RH, et al. Progress and challenges in metabolic syndrome in children and adolescents: a scientific statement from the American Heart Association Atherosclerosis, Hypertension, and Obesity in the Young Committee of the Council on Cardiovascular Disease in the Young; Council on Cardiovascular Nursing; and Council on Nutrition, Physical Activity, and Metabolism. Circulation. Feb 3 2009;119(4):628-647.